Pathomechanisms of renal Fabry disease
The result: conventional oral glutathione supplementation produces negligible direct elevation of intracellular GSH levels
This can happen for a few reasons
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Use of phosphate-based fertilizers which contain arsenic, cadmium, lead in trace amount, use of untreated sewage that contained the heavy metals as fertilizers, contaminated run-off from mining and smelting industries near agricultural farmlands, industrial wastes from manufacturing industries that leach into the soil, urban construction also introduce heavy metals to the soil, chemical spills, landfill leakage, recycling of materials, atmospheric deposition, weathering and erosion as well as other natural processes (Adamu et al
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